Numerous studies have shown oregano to be effective in killing a number of bacterial
pathogens including Klebsiella, E.coli, Salmonella, H.pylori and Staphylococcus
aureus. The active phenolic components of oregano oil are thought to kill bacteria by
altering their membrane and cell wall integrity. Bacterial dysiosis, or an imbalance
between good and bad gut flora, is commonplace in conditions such as abdominal
bloating, flatulence, IBS and leaky gut disorder and a variety of other conditions.
Eradication of pathogenic bacteria, whilst promoting the probiotic bacteria, is a basic
strategy in all these conditions. Importantly, oregano does not appear to adversely
affect levels of good bacteria in the gut.
Due to its content of alkaloids (e.g. hydrastine, berberine, canadine), goldenseal exerts
a broad spectrum of anti-bacterial activity against pathogens such as staphylococcus,
streptomyces, chlamydia, corynebacterium diphtheria, escherichia coli, salmonella
typhi, vibrio cholera, etc. In addition, goldenseal may promote intestinal homoeastasis
by inhibiting the formation of toxic polyamines, which are formed from incompletely
digested proteins by the action of certain bacteria causing inflammation and damage to
intestinal wall integrity.
Garlic exerts broad-spectrum anti-microbial activity against a variety of pathogens
including; viruses, bacteria, fungi e.g. candida species, and parasites. Garlic has a
history of being used to kill bacteria and control secondary fungal infections; detoxify
and gently stimulate elimination. It also has antioxidant properties that offer protection
against oxidation caused by bacterial toxins.
The fibre content of the diet is a key determinant in the health of the gut. A high fibre
diet promotes probiotic organisms that help to control the level of pathogens in the
gut, including parasites, candida, and pathogenic (bad) bacteria. In the case of an
existing bacterial infection fibre is helpful, in combination with antibiotic herbs, in the
removal of toxins and the restoration of good gut ecology.
Through the fermentation of fibre in the gastrointestinal tract, probiotics are able to
produce various organic acids. These acids have the effect of reducing the pH
(increasing the acidity) of the intestines and as such make the environment undesirable
for resident and non-resident pathogenic bacteria, parasites and yeasts. When used in
combination with antimicrobial herbs, probiotics help to ensure that healthy gut
ecology is restored, thus ensuring better resistance to future infection.
Intestinal Dysbiosis Summary
Nutrient/Herb Typical intake range
Oregano Oil1 15 – 45mg per day
Goldenseal extract (10% alkaloids)1,2 150 – 600mg per day
Garlic1,3 80 – 160mg macerate per day
Psyllium husk fibre 3 – 6g per day with glass of water
Probiotics 5 – 15 billion organisms per day
Saturated and trans fats
Nuts and seeds
High fibre, low saturated fat diets promote healthy intestinal ecology
Wash hands to avoid hand-to-mouth infection (most common route of infection)
1. Do not use in pregnancy or lactation.
2. Do not use concurrently with antiarrhythmics, anticoagulants, anti-hypertensives, or beta blockers
without medical supervision. May disrupt B-vitamin absorption – use with B-complex.
3. Do not use with warfarin or anticoagulant medication. Concurrent use with insulin and oral antidiabetic
medication under medical supervision only.